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Table of Contents > Drug > Alendronate and Cholecalciferol Print

Alendronate and Cholecalciferol

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Fosamax Plus D
    • Brand Names: Canada: Fosavance
    • Mexican Brand Names: Fosamax Plus
    • Pharmacologic Category: Bisphosphonate Derivative;Vitamin D Analog

    Uses
    • It is used to put off or treat soft, brittle bones (osteoporosis).
    • Alendronate lowers bone loss.
    • Cholecalciferol acts as a hormone to control how much calcium is stored in the body.

    Dosing

    How to take

    • Take on an empty stomach before breakfast.
    • Take with a full glass of water at least 30 minutes before the first food, drink, or drugs of the day.
    • Take with plain water only. Avoid taking with mineral water or other drinks.
    • Swallow tablet whole. Do not chew, break, or crush.
    • Do not lie down for at least 30 minutes after taking this drug. This stops irritation to the swallowing tube (esophagus).
    • This drug works best when used with calcium/vitamin D and weight-bearing workouts like walking or PT (physical therapy).
    • Follow the diet and workout plan that your doctor told you about.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Protect from light.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to alendronate, vitamin D, cholecalciferol, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: A swallowing tube (esophagus) that is not normal, low calcium levels, or trouble swallowing.
    • If you are not able to stand or sit up for 30 minutes.
    • If you have a malabsorption syndrome or too much vitamin D or calcium in your body.

    Precautions

    • If you have had high calcium levels, talk with your doctor.
    • If you have GI (gastrointestinal) disease, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have leukemia or lymphoma, talk with your doctor.
    • If you have sarcoidosis, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Do not take cholestyramine, mineral oil, antacids that have magnesium, or orlistat with this drug.
    • If you are taking other sources of vitamin D, talk with your doctor.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Take good care of your teeth. See a dentist often.
    • Have a bone density test. Talk with your doctor.
    • Avoid beer, wine, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Belly pain or heartburn.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • High calcium level. Signs include weakness, confusion, feeling tired, headache, upset stomach and throwing up, hard stools (constipation), or bone pain.
    • Bone, joint, or muscle pain may rarely happen.
    • A broken leg may rarely happen.
    • Harm to the jaw bone may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain.
    • Very bad belly pain.
    • Trouble swallowing.
    • Very upset stomach or throwing up.
    • Very bad jaw pain.
    • Very bad bone, joint, or muscle pain.
    • Very bad groin or thigh pain.
    • Numbness or tingling in your mouth.
    • Numbness or tingling in your hands or feet.
    • Twitching.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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