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Table of Contents > Drug > Aldesleukin Print

Aldesleukin

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Proleukin®
    • Brand Names: Canada: Proleukin®
    • Pharmacologic Category: Antineoplastic Agent, Miscellaneous;Biological Response Modulator

    Uses
    • It is used to treat kidney cancer.
    • It is used to treat skin cancer.
    • Aldesleukin helps fight cancer.

    Dosing

    How to take

    • It is given as a shot into the fatty part of the skin.
    • It is given into a vein for a period of time.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

    Missed Dose

    • Call your doctor to find out what to do.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • This drug is very strong. It may cause very bad low blood pressure and harm to your organs. Tell your doctor if you have any heart or lung disease. Very bad infections may happen with use of this drug. Tell your doctor right away if you feel very sleepy or weak.
    • Closely read the part in this leaflet which lists when to call your doctor. You will be closely watched by your doctor.
    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to aldesleukin or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Bleeding from the stomach or bowel, coma, dialysis, a fast heartbeat, heart disease, hole in the GI (gastrointestinal) tract, lung disease, organ transplant, or seizures.
    • If you are breast-feeding.

    Precautions

    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of a very bad infection or make the vaccine not work as well.
    • If you have an immune or inflammatory disease, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you are having an x-ray with dye, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Chance of getting an infection. Avoid people with infections, colds, or flu.
    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Low blood pressure.
    • Belly pain.
    • Cough.
    • Loose stools.
    • Mouth irritation. Using a soft toothbrush or cotton swabs and rinsing the mouth may help.
    • Weight gain.
    • Feeling tired or weak.
    • Anemia, low white blood cell count, and low platelet count. This drug may need to be stopped.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Chest pain or pressure or a fast heartbeat.
    • Very bad dizziness or passing out.
    • Trouble breathing.
    • Change in thinking clearly and with logic.
    • Swelling in your legs or belly.
    • A big weight gain.
    • Very bad belly pain.
    • Not able to pass urine.
    • Not able to eat.
    • Any bruising or bleeding.
    • Yellow skin or eyes.
    • Feeling very tired or weak.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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