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Table of Contents > Drug > Donepezil Print

Donepezil

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • U.S. Brand Names: Aricept®;Aricept® ODT
    • Canadian Brand Names: Aricept®;Aricept® RDT
    • Mexican Brand Names: Eranz
    • Pharmacologic Category: Acetylcholinesterase Inhibitor (Central)

    Uses
    • This medicine is used to treat Alzheimer's disease.
    • Donepezil increases the amount of a chemical called acetylcholine in the brain. Acetylcholine may be involved in memory, attention, and learning.

    Dosing

    How to take

    • Take this medicine at bedtime.
    • Take this medicine with or without food. Take with food if it causes an upset stomach.
    • Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
    • Swallow tablet whole. Do not chew, break, or crush.
    • Oral-disintegrating tablet: Place on tongue and let dissolve. Do not swallow whole.

    Missed Dose

    • Take a missed dose as soon as possible.
    • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
    • Do not take a double dose or extra doses.
    • Do not change dose or stop medicine. Talk with healthcare provider.

    Storage

    • Store at room temperature.
    • Protect from moisture. Do not store in a bathroom or kitchen.

    Safety



    Avoid

    • If you have an allergy to donepezil or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
    • If you are breast-feeding.

    Precautions

    • If you have lung disease, talk with healthcare provider.
    • If you have seizures, talk with healthcare provider.
    • If you have a slow heartbeat, talk with healthcare provider.
    • If you have had an ulcer or bleeding from your stomach or intestines, talk with healthcare provider.
    • If you have urinary tract blockage, talk with healthcare provider.
    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Avoid alcohol (includes wine, beer, and liquor).
    • Tell healthcare provider if you are pregnant or plan on getting pregnant.

    Side Effects

    • Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
    • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Diarrhea.
    • Headache.
    • Inability to sleep.
    • Not hungry.
    • Weight loss.

    Monitoring

    • Change in condition being treated. Is it better, worse, or about the same?
    • Follow up with healthcare provider.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.
    • Difficulty breathing.
    • Severe dizziness or passing out.
    • Severe nausea or vomiting.
    • Severe diarrhea.
    • Unusual bruising or bleeding.
    • Significant weight loss.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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