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Table of Contents > Drug > Guaifenesin, Pseudoephedrine, and Dextromethorphan Print

Guaifenesin, Pseudoephedrine, and Dextromethorphan

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Ambifed DM;Ambifed-G DM;ExeFen-DMX;Maxifed DM;Maxifed DMX
    • Brand Names: Canada: Balminil DM + Decongestant + Expectorant;Benylin® DM-D-E

    Uses
    • It is used to make a cough productive.
    • It is used to stop coughing.
    • It is used to treat nose stuffiness.
    • Guaifenesin thins fluids in the lungs.
    • Pseudoephedrine shrinks swollen nose tissue and opens up passages.
    • Dextromethorphan works on the cough center in the brain.

    Dosing

    How to take

    • Take with or without food. Take with food if it causes an upset stomach.
    • Long-acting products: Swallow whole. Do not chew, break, or crush.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • There is a liquid if you cannot swallow pills.
    • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Many times this drug is taken on an as needed basis.

    Storage

    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Talk with the doctor before giving this drug to a child. Check all of your child's drugs, including OTC, with doctor.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

    Avoid

    • If you have an allergy to guaifenesin, pseudoephedrine, dextromethorphan, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Very bad heart disease or very high blood pressure.
    • If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this drug is started. Taking both at the same time could cause risky high blood pressure.

    Precautions

    • This drug is not for coughs due to smoking or lung disease.
    • If you have high blood pressure, talk with your doctor.
    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have glaucoma, talk with your doctor.
    • If you have heart disease, talk with your doctor.
    • If you have trouble passing urine, talk with your doctor.
    • If you have thyroid disease, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Nervous and excitable.
    • Not able to sleep.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain or pressure, a fast heartbeat, or passing out.
    • Very bad headache.
    • Cough that does not go away.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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