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Table of Contents > Drug > Interferon Gamma-1b Print

Interferon Gamma-1b

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Actimmune®
    • Brand Names: Canada: Actimmune®
    • Pharmacologic Category: Interferon

    Uses
    • It is used to fight infections having to do with chronic granulomatous disease.
    • It is used to slow the progress of osteopetrosis.
    • Interferon gamma-1b helps fight infections.

    Dosing

    How to take

    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Take at bedtime to help with flu-like signs.
    • Move the site where you give the shot with each shot.
    • Follow how to give closely if you or a family member is giving the shot at home.
    • Wash your hands before and after use.
    • Do not shake the solution.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose, brand, or stop this drug. Talk with the doctor.

    Storage

    • Store in a refrigerator. Do not freeze.
    • Do not shake.
    • Throw away any part of opened vial not used after use.

    Safety



    Avoid

    • If you have an allergy to interferon gamma-1b, E. coli-derived proteins, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • If you have bleeding problems, talk with your doctor.
    • If you have heart disease, talk with your doctor. The flu-like side effects of interferon may be stressful to heart patients.
    • If you have seizures, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Irritation where the shot is given.
    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
    • Loose stools.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Belly pain.
    • Muscle weakness.
    • Low mood (depression).

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
    • Any bruising or bleeding.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • Not able to eat.
    • Very upset stomach or throwing up.
    • Very bad belly pain.
    • Very bad skin irritation.
    • If you get pregnant while taking this drug.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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