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Table of Contents > Drug > Minocycline Print



Related terms
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    Related terms
    • Brand Names: U.S.: Dynacin®;Minocin®;Minocin® PAC;Solodyn®
    • Brand Names: Canada: Apo-Minocycline®;Arestin Microspheres;Dom-Minocycline;Minocin®;Mylan-Minocycline;Novo-Minocycline;PHL-Minocycline;PMS-Minocycline;ratio-Minocycline;Riva-Minocycline;Sandoz-Minocycline

    • It is used to stop or treat bacterial infections.
    • Minocycline works to harm the bacteria and fight the infection.


    How to take

    • To gain the most benefit, do not miss doses.
    • Use as you have been told, even if you are feeling better.
    • Oral:
    • Take with or without food. Take with food if it causes an upset stomach.
    • Take with a full glass of water.
    • Do not lie down for at least 30 minutes after taking this drug. This stops irritation to the swallowing tube (esophagus).
    • Long-acting tablet: Swallow it whole. Do not chew, break, or crush it.
    • Shot:
    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store at room temperature.
    • Protect capsules and tablets from water. Do not store in a bathroom or kitchen.
    • Throw away any unused part of this drug.
    • The shot will be given to you in a hospital or doctor's office. You will not store it at home.



    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to minocycline or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.


    • If you have kidney disease, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not take bismuth (Pepto-Bismol®), calcium, iron, magnesium, zinc, multivitamins with minerals, colestipol, cholestyramine, didanosine, or antacids within 2 hours of this drug.
    • Avoid beer, wine, or mixed drinks.
    • You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Belly pain.
    • Irritation where the shot is given.
    • Not hungry.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea). Yogurt or probiotics may help. You may get these products at health food stores or in some pharmacies.
    • For women, vaginal yeast infection. Report itching or discharge.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad headache.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea), even after drug is stopped.
    • Big change in balance.
    • Ringing in ears.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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