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Table of Contents > Drug > Minocycline Hydrochloride Periodontal Microspheres Print

Minocycline Hydrochloride Periodontal Microspheres


Related terms
Author information


    Related terms
    • U.S. Brand Names: Arestin®
    • Pharmacologic Category: Antibiotic, Tetracycline Derivative

    • This medicine is used to treat adult periodontitis. It is used with scaling and root planing.
    • Minocycline works to injure the bacteria and fight the infection.


    How to take

    • This medicine will be given to you by a healthcare provider.

    Missed Dose

    • Call healthcare provider for appointment.


    • This medicine will be given to you in a healthcare setting. You will not store it at home.



    • If you have an allergy to minocycline or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
    • If you are pregnant or may be pregnant.


    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Do not chew hard, crusty, or sticky foods.
    • Do not brush or floss near the area for 12 hours.
    • You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
    • Use birth control that you can trust to prevent pregnancy while taking this medicine.
    • Tell healthcare provider if you are breast-feeding.

    Side Effects

    • Discomfort around placement area.
    • Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.
    • Headache.


    • Change in condition being treated. Is it better, worse, or about the same?
    • Follow up with healthcare provider.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Severe pain, swelling, or bleeding at treatment area.
    • Severe diarrhea, even after medicine is stopped.
    • Severe headache.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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