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Table of Contents > Drug > Trimipramine Print

Trimipramine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • U.S. Brand Names: Surmontil®
    • Canadian Brand Names: Apo-Trimip®;Nu-Trimipramine;Rhotrimine®;Surmontil®
    • Pharmacologic Category: Antidepressant, Tricyclic (Tertiary Amine)

    Uses
    • It is used to treat low mood (depression).
    • Trimipramine raises chemicals in the brain.
    • In low mood (depression), sleep and appetite may get better fast. Other signs may take up to 4 to 6 weeks to get better.

    Dosing

    How to take

    • Take at bedtime if it causes sleepiness.
    • Take with or without food. Take with food if it causes an upset stomach.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to time for the next dose, skip the missed dose and return to your normal time.
    • Do not take two doses or extra doses.
    • Do not change dose or stop drug. Talk with doctor.

    Storage

    • Store at room temperature.
    • Protect from light.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • The want to harm yourself is a not safe sign of low mood (depression). It may last until your low mood is fully treated. If you are planning on harming yourself, call the ER (emergency department) right away.
    • Unsafe reactions may happen. This drug cannot be taken while you are taking certain other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to trimipramine or any other part of this drug.
    • Tell doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs involved.
    • If you have had a recent heart attack.
    • If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this drug is started. Taking the two at the same time could cause risky high blood pressure.
    • If you are breast-feeding.

    Precautions

    • If you are 65 or older, use this drug with care. You could have more side effects.
    • If you have been taking this drug for many weeks, talk with doctor before stopping. You may want to little by little stop this drug.
    • If you have high blood sugar (diabetes), talk with doctor.
    • If you have heart disease, talk with doctor.
    • If you have an overactive thyroid, talk with doctor.
    • If you have seizures, talk with doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with certain other drugs.
    • You may not be alert. Avoid driving, doing other tasks or activities until you see how this drug affects you.
    • Avoid alcohol (includes wine, beer, and liquor) or other drugs and natural products that slow your actions and reactions.
    • Avoid grapefruit and grapefruit juice.
    • You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
    • Tell doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving, doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes from sitting or lying position. Be careful climbing.
    • Constipation. More liquids, regular exercise, or a fiber diet may help. Talk with doctor about a stool softener or laxative.
    • Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

    Monitoring

    • Change in health problem being treated. Is it better, worse, or about the same?
    • Dry mouth may cause more cavities. Take good care of your teeth. See a dentist often.
    • Follow up with doctor.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • If you are planning to harm yourself or the want to harm yourself gets worse.
    • Fast heartbeat.
    • Very bad dizziness or passing out.
    • Big change in thinking clearly and with logic.
    • Unable to pass urine.
    • Very nervous and excitable.
    • Feeling very tired or weak.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, supplements, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for health help about side effects. You may also call the FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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